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Matthew B Dobbs Selected Research

Clubfoot (Talipes Equinovarus)

1/2022Clubfoot.
1/2022Whole Exome Sequencing in Individuals with Idiopathic Clubfoot Reveals a Recurrent Filamin B (FLNB) Deletion.
6/2017The 2017 ABJS Nicolas Andry Award: Advancing Personalized Medicine for Clubfoot Through Translational Research.
3/2017Design and descriptive data of the randomized Clubfoot Foot Abduction Brace Length of Treatment Study (FAB24).
1/2016Does Strict Adherence to the Ponseti Method Improve Isolated Clubfoot Treatment Outcomes? A Two-institution Review.
5/2014Genome-wide association study identifies new disease loci for isolated clubfoot.
4/2013Copy number analysis of 413 isolated talipes equinovarus patients suggests role for transcriptional regulators of early limb development.
10/2011Pitx1 haploinsufficiency causes clubfoot in humans and a clubfoot-like phenotype in mice.
9/2011Variants in genes that encode muscle contractile proteins influence risk for isolated clubfoot.
6/2011Exome sequencing identifies an MYH3 mutation in a family with distal arthrogryposis type 1.
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Matthew B Dobbs Research Topics

Disease

21Clubfoot (Talipes Equinovarus)
01/2022 - 07/2004
11Scoliosis
04/2020 - 02/2004
11Congenital Abnormalities (Deformity)
10/2018 - 06/2004
7Cerebral Palsy (Spastic Diplegia)
08/2020 - 03/2017
7Flatfoot (Flat Feet)
06/2017 - 11/2005
6Pain (Aches)
08/2020 - 07/2003
4Arthrogryposis
01/2022 - 05/2009
3Contracture
11/2020 - 06/2011
3Muscle Spasticity (Spastic)
08/2020 - 01/2020
3Femoral Fractures (Femoral Fracture)
08/2020 - 08/2004
3Pseudarthrosis (Pseudoarthrosis)
07/2018 - 06/2004
2Marfan Syndrome (Marfan's Syndrome)
09/2015 - 10/2014
1Cap Myopathy
01/2022
1Congenital Structural Myopathies (Centronuclear Myopathy)
01/2022
1Megalencephaly
01/2021
1Syringomyelia (Morvan's Disease)
04/2020
1Congenital torticollis
05/2019
1Spondylolysis
10/2018
1Kyphosis
10/2018
1Spondylolisthesis
10/2018
1Spinal Curvatures (Spinal Curvature)
10/2018
1Synostoses, tarsal, carpal, and digital
10/2017
1Loeys-Dietz Syndrome
09/2015
1Aortic Aneurysm (Aneurysm, Aortic)
09/2015
1Hip Dislocation
02/2013
1Ulna Fractures
09/2012
1distal type 1 Arthrogryposis multiplex congenita
06/2011
1familial horizontal gaze palsy with progressive scoliosis
04/2011
1Rare Diseases (Rare Disease)
04/2011
1Tailor's Bunion
12/2010
1Infections
10/2009
1Distal arthrogryposis type 2B
05/2009
1Foot Deformities (Foot Deformity)
05/2009
1Freeman-Sheldon syndrome
05/2009
1Knee Dislocation
06/2008
1Larsen Syndrome
06/2008
1Tibial Fractures (Fracture, Tibial)
06/2007
1Osteomyelitis
03/2005
1Infectious Arthritis (Septic Arthritis)
03/2005

Drug/Important Bio-Agent (IBA)

4DNA (Deoxyribonucleic Acid)IBA
05/2014 - 09/2010
3Transcription Factors (Transcription Factor)IBA
04/2013 - 07/2010
3Proteins (Proteins, Gene)FDA Link
04/2013 - 04/2011
2Pain-FreeIBA
01/2022 - 08/2020
2FilaminsIBA
01/2022 - 06/2008
2TropomyosinIBA
01/2022 - 05/2009
2Myosins (Myosin)IBA
11/2020 - 06/2011
2Biological ProductsIBA
06/2017 - 12/2009
2TitaniumIBA
09/2012 - 06/2007
2EnzymesIBA
07/2011 - 09/2010
2Growth Differentiation Factor 5IBA
05/2009 - 11/2005
1Microfilament Proteins (Actin Binding Proteins)IBA
01/2022
1Codon (Codons)IBA
01/2022
1P-2 (P 2)IBA
01/2021
1Botulinum Toxins (Botulinum Toxin)IBA
05/2019
1ManganeseIBA
10/2018
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
07/2018
1bone waxIBA
10/2017
1Biomarkers (Surrogate Marker)IBA
06/2017
1Transforming Growth Factor-beta Type II ReceptorIBA
09/2015
1Transforming Growth Factor-beta Type I ReceptorIBA
09/2015
1Nonsense Codon (Nonsense Mutation)IBA
09/2015
1Transforming Growth Factor beta (TGF-beta)IBA
10/2014
1MorpholinosIBA
12/2013
1Contractile ProteinsIBA
09/2011
1Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
07/2011
1Melatonin Receptors (Melatonin Receptor)IBA
09/2010
1Serotonin (5 Hydroxytryptamine)IBA
09/2010
1Hormones (Hormone)IBA
09/2010
1MelatoninIBA
09/2010
1Anti-Bacterial Agents (Antibiotics)IBA
10/2009
1Povidone-Iodine (Betadine)FDA LinkGeneric
10/2009
1Troponin T (Troponin T1)IBA
05/2009
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
05/2009
14-(N-maleimido)benzyltrimethylammonium (MPTA)IBA
04/2009
13' Untranslated Regions (3' UTR)IBA
09/2007

Therapy/Procedure

8Braces
08/2020 - 07/2007
7Rhizotomy
08/2020 - 03/2017
7Tenotomy
01/2020 - 07/2004
3Intramedullary Fracture Fixation
08/2020 - 08/2004
3Surgical Casts (Plaster Cast)
03/2007 - 07/2004
2Orthopedic Procedures
08/2020 - 07/2019
2Orthotic Devices (Orthosis)
10/2013 - 07/2007
2Osteotomy
02/2013 - 12/2010
2Spinal Fusion (Spondylosyndesis)
09/2006 - 02/2004
2Length of Stay
03/2005 - 08/2004
2Surgical Amputation (Amputations)
03/2005 - 06/2004
2Bone Transplantation (Bone Grafting)
03/2005 - 06/2004
1Decompression
04/2020
1Physical Therapy Modalities (Physical Therapy Technique)
05/2019
1Laminoplasty
10/2018
1Laminectomy
10/2018
1Therapeutics
06/2017
1Precision Medicine
06/2017
1Conservative Treatment
01/2016
1Pinealectomy
09/2010
1Reoperation
01/2008
1Pedicle Screws
09/2006
1Aftercare (After-Treatment)
05/2006
1Fasciotomy
05/2006
1Debridement
03/2005